Journal: Nature Communications

Article Title: Ultra-conformal drawn-on-skin electronics for multifunctional motion artifact-free sensing and point-of-care treatment

doi: 10.1038/s41467-020-17619-1

Figure Lengend Snippet: a DoS electronics drawing process beginning with (i) a tape-based stencil attachment to the skin (scale bar 1 cm), (ii) drawing the device with the stencil, modified ballpoint pen, and inks (scale bar 5 mm), inset is a closeup of the tip (scale bar 1 mm), (iii) removal of the stencil (scale bar 2 cm), and (iv) the completed device after drying (scale bar 1 cm). b An example DoS integrated system including a resistor, transistors, heater, EP (electrophysiological) sensors, temperature sensor, strain sensor, and skin hydration sensor drawn on human skin (scale bar 5 mm). The corresponding stencil for the conductor is shown in the inset (scale bar 1 cm). c Achievable line spacing using stencils and the conductive Ag-PEDOT:PSS ink (scale bar 1 mm). d Non-stretched (left, scale bar 1 mm) and biaxially stretched (right, scale bar 1 cm) states of the drawn structure consisting of Ag-PEDOT:PSS conductive (left square) and P3HT-NF semiconducting (right square) inks on PDMS. e Twisting (left) and poking (right, scale bars 1 cm) deformations of the drawn structure with conductive and semiconducting inks. f SEM images of the Ag-PEDOT:PSS ink showing ultraconformal contact with the grooves and bumps (left, scale bar 250 µm) on top of skin replica and cross-section showing Ag-PEDOT:PSS microstructure (right, scale bar 20 µm). The purple color indicates the skin replica. g Histology image of the Ag-PEDOT:PSS ink on skin of mice after 48 h (scale bar 100 µm). h Histology image of the P3HT-NF ink on skin of mice after 48 h (scale bar 100 µm). i Sheet resistance vs. strain while stretching the Ag-PEDOT:PSS ink up to 30% and releasing. The error bars represent the s.d. j Optical microscope images of the Ag-PEDOT:PSS ink on skin replica stretched up to 30% (scale bars 100 µm). k DoS EP sensor on the wrist of subject in stretched (top) and non-stretched (bottom) states (scale bars 5 mm).

Article Snippet: Double-sided conductive acrylic tape (ARclad® 8001–77, Adhesives Research), cut to approximately the same dimensions as the DoS EP sensor, was laminated onto the sensors, and electrical leads were attached to the conductive tape.

Techniques: Modification, Microscopy

Journal: Nature Communications

Article Title: Ultra-conformal drawn-on-skin electronics for multifunctional motion artifact-free sensing and point-of-care treatment

doi: 10.1038/s41467-020-17619-1

Figure Lengend Snippet: a Schematic of the DoS transistor based on the Ag-PEDOT:PSS ink as the conductor, P3HT-NF ink as the semiconductor, and ionic gel ink as the dielectric. b DoS transistor on skin replica under no strain (top) and 30% strain (bottom, scale bars 5 mm). c SEM image of the drawn source (S) and drain (D) electrodes and the channel (scale bar 100 µm). d I-V curve of DoS transistor without applied strain. e , f Transfer curves of DoS transistor without and 30% strain along the transistor channel length direction. g Electrical resistance of the DoS strain sensor under applied mechanical strain up to 30% and the corresponding gauge factors. Inset shows a schematic of the DoS strain sensor. The error bars represent the s.d. h Relative resistance change of the DoS strain sensor under cyclic stretching and releasing at 10% and 25% strain. i Relative resistance change of the DoS temperature sensor under different temperature conditions. j Schematic of the DoS heater based on the conductive ink. k Temperature profiles under different applied voltage on the DoS heater. l Calibration curve of the DoS heater. The error bars represent the s.d.

Article Snippet: Double-sided conductive acrylic tape (ARclad® 8001–77, Adhesives Research), cut to approximately the same dimensions as the DoS EP sensor, was laminated onto the sensors, and electrical leads were attached to the conductive tape.

Techniques:

Journal: Nature Communications

Article Title: Ultra-conformal drawn-on-skin electronics for multifunctional motion artifact-free sensing and point-of-care treatment

doi: 10.1038/s41467-020-17619-1

Figure Lengend Snippet: a Experimental setup showing DoS electrodes around a skin wound on the back of mice ( N = 3). The DoS electrodes served as conductive paths for electrical stimulation (scale bar 2 cm). b Photos of the wound healing on day 1 (left), day 3 (middle) and day 5 (right). Top half of the wound was treated with electrical stimulation while the bottom half was left untreated and healed naturally (scale bar 1 cm). c Histology images of the treated (top, scale bar 100 µm) and untreated (bottom, scale bar 250 µm) halves of the wound on day 5. The black arrows indicate the width of the wound. d Scab width over time for the treated (black) and untreated (red) halves of the wound.

Article Snippet: Double-sided conductive acrylic tape (ARclad® 8001–77, Adhesives Research), cut to approximately the same dimensions as the DoS EP sensor, was laminated onto the sensors, and electrical leads were attached to the conductive tape.

Techniques: